Large adult dogs have a relatively small digestive apparatus and thus limited digestive capacity. Their intestinal walls are more permeable than those of small dogs, enabling more water to enter the intestines and thus cause a higher water content in stool. Increased fermentation of colon bacteria may also lead to flatulence in large dogs.

Because of their unique characteristics, large dogs not only have a delicate digestive system but also sensitive joints. Excessive exercise, especially of young dogs, may cause early damage to bones and joints.

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